The plant Caesalpinia bonducella is used for a variety of biological activities. In view of its broad pharmacological significance in Ayurveda, we screened the leaves and steam bark extracts for antiulcer activity. The antiulcer activity was evaluated at concentrations of 400 and 800 mg/kg body weight, ranitidine at 50 mg/kg body weight was used as standard. The antiulcer effect exhibited by ethanol extract at 800 mg/kg body weight was comparable with ranitidine treated group at 50 mg/kg body weight. The activity exhibited by the ethanol extract was dose-dependent. The results indicate the potentialality of the ethanol extract of Caesalpinia bonducella as anti-ulcerogenic.
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